Human iPS-Derived Cerebral Cortex Neurons : 2012

Photograph by

Roberta Cagnetta

About this image

Confocal light micrograph of human cerebral cortex neurons. The core of each neuron is about 15 micrometres across. These nerve cells have been infected by a lentivirus that expresses Green Fluorescent Protein (GFP). The sample has been stained with fluorescent markers that bind to different structures. Blue areas are DAPI, a stain that binds strongly to DNA; green marks the GFP inside virus-infected cells; purple areas show the antibody Tuj1 that binds with neurites, projections from the cell body of the neuron. The neurons seen here were grown from induced pluripotent stem (iPS) cells. Stem cell research is aimed at providing possible new treatments for debilitating degenerative conditions such as Alzheimer’s. The Henry Wellcome Building of Cancer and Developmental Biology, University of Cambridge, Cambridge, United Kingdom